What is the main effect of ACE II in relation to blood pressure?

What is the main effect of ACE II in relation to blood pressure?

• A. Increase blood pressure
• B. Regulate oxygen levels
• C. Lower blood pressure
• D. Enhance ventilation

Answer: (C)

ACE II, or angiotensin-converting enzyme II, plays a critical role in the renin-angiotensin system, which is vital for regulating blood pressure. Its primary effect is to lower blood pressure. ACE II acts by converting angiotensin II, a vasoconstrictor, back to angiotensin 1-7, a peptide that induces vasodilation, promotes natriuresis (excretion of sodium in the urine), and enhances bradykinin levels, which also contribute to reduced blood pressure. By counterbalancing the effects of angiotensin II, ACE II helps to maintain blood pressure within a healthy range. Understanding this function of ACE II is essential for comprehending how certain medications targeting this pathway can be used to treat hypertension and other cardiovascular-related conditions.

ACE II, or angiotensin-converting enzyme II, plays a critical role in the renin-angiotensin system, which is vital for regulating blood pressure. Its primary effect is to lower blood pressure. ACE II acts by converting angiotensin II, a vasoconstrictor, back to angiotensin 1-7, a peptide that induces vasodilation, promotes natriuresis (excretion of sodium in the urine), and enhances bradykinin levels, which also contribute to reduced blood pressure.

By counterbalancing the effects of angiotensin II, ACE II helps to maintain blood pressure within a healthy range. Understanding this function of ACE II is essential for comprehending how certain medications targeting this pathway can be used to treat hypertension and other cardiovascular-related conditions.